archives@tulane.edu / Primary hemostasis is a process in which platelet plugs form to stop bleeding immediately following injury to the vascular wall. Platelet activation and aggregation work hand-in-hand to form these platelet plugs, and the study of these processes is crucial for diagnosing coagulopathies. Light transmission aggregometry is a primary in-vitro test clinicians use for evaluating platelets' ability to form aggregates in response to stimulation by a soluble agonist. However, these tests often employ large volumes of blood. This study aims to create a system for small-volume, non-contact light transmission aggregometry using acoustic levitation, and additionally aims to test such a system on platelet aggregation models using polystyrene microspheres, and then, platelet-rich plasma itself. / 1 / Jeremy Chinwe Orie
| Identifer | oai:union.ndltd.org:TULANE/oai:http://digitallibrary.tulane.edu/:tulane_122479 |
| Date | January 2021 |
| Contributors | Orie, Jeremy Chinwe (author), Khismatullin, Damir (Thesis advisor), School of Science & Engineering Biomedical Engineering (Degree granting institution) |
| Publisher | Tulane University |
| Source Sets | Tulane University |
| Language | English |
| Detected Language | English |
| Type | Text |
| Format | electronic, pages: 53 |
| Rights | No embargo, Copyright is in accordance with U.S. Copyright law. |
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