(I) Sugars Content of Honey from Wild and Kept Honeybees (II) Studies on the Photodegradation Products of Indomethacin / (I)野生蜂與養殖蜂所產蜂蜜的糖類含量分析(II)Indomethacin光解產物的探討

碩士 / 台北醫學院 / 藥學研究所 / 82 / The purpose of the first part of this study was to analyze
major sugar components of honey by high performance liquid
chromatography (HPLC) method. Results, compared with data
obtained from similar studies in Poland, the United States, and
Canada, showed no obvious discrepancies. Results indicated that
the fructose content in honey collected from kept honeybees was
38% ; in winter honey, 36% and from wild honeybees, 45 %. The
glucose content in winter honey was 27%; in kept honey, 33 % ;
and wild honey, 31%. Thus, the fructose- to-glucose ratios are
between 1.1-1.2 in kept honey and 1.4-1.6 in wild honey. Only a
small amount of sucrose was detectable in some samples, while
the content of maltose in all samples was around 4.2 %. The
total sugar content in winter honey was 67%; honey produced in
other seasons contained 75%, with wild honey up to 80 % . The
second part, gives a preliminary study of photodegrada- tion
pathway of indomethacin. In the past, there seems no clear
reports on photodegradation of indomethacin in organic
solvents. The present author obtained a major photodegraded
product from indomethacin in chloroform solution after exposure
to sunshine by the column chromatography. Its structure was
identified by means of NMR, IR and MS. Some information of
others photodegrad- ed products were also found. Generally,
indomethacin proceeded a photooxydation reaction pathway in
chloroform and methanol under sunshine. These photodegraded
products seem unstable under high temperature and proceed to
further complex degradation.

Identiferoai:union.ndltd.org:TW/082TMC00551006
Date January 1994
CreatorsTzu Chang Chou, 周子昌
ContributorsChau Yang Chen, 陳朝洋
Source SetsNational Digital Library of Theses and Dissertations in Taiwan
Languagezh-TW
Detected LanguageEnglish
Type學位論文 ; thesis
Format4

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