碩士 / 台北醫學院 / 保健營養學研究所 / 88 / ABSTRACT
The effects of chlorella on the lipid metabolism in Wistar male rats were investigated in this study. Two different feed regiments were designed to test the hypolipidemic function of chlorella. In the first regiments, chlorella (0%,1%, 5% and 10%) was added to the high fat and high cholesterol diet at the same time for feeding normal rats, and prevention of hyperlipidemia by chlorella was tested(testⅠ).In the second regiment, chlorella (0%,1%, 5% and 10%)was added to the diet for feeding the hyperlipidemia in rats, and the hypolipidemic effects of chlorella were investigated(testⅡ).In the test Ⅰthe results showed that the concentrations of plasma total cholesterol, triglyceride and LDL-C were significantly lower in1%,5% and 10% group than 0% group. In liver lipid contents, the concentrations of cholesterol and triglyceride in 1%,5% and 10% group were also significantly lower than 0% group（↓30%、68%、77%；50%、67%、68%）. However , cholesterol and bile acid in feces had not significantly different in each group. In the test Ⅱ, the results showed that the concentrations of plasma lipid were also higher in 0%chlorella group after a 8-week normal diet. However, the decrease of the plasma total cholesterol ,triglyceride and LDL-C and the increase of plasma HDL-C were faster in 1% ,5% and 10%chlorella group than in 0% group. Furthermore, the inhibition of cholesterol and triglycerid accumulation were also observed in chlorella feeding group（TC↓63%、62%、51%；TG↓61%、73%、81%）. Therefore, chlorella exactly has the hypolipidemic functions and inhibits the cholesterol and triglycerid accumulation in liver.
Key word: chlorella、hyperlipidemia、plasma lipid
| Identifer | oai:union.ndltd.org:TW/088TMC00217007 |
| Date | January 2000 |
| Creators | Ti-I Huang, 黃娣儀 |
| Contributors | Suh-Ching Yang, 楊素卿 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 96 |
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