Cytotoxic Constituents from Formosan Soft Coral Clavularia violacea / 綠島產紫羽珊瑚癌細胞毒殺成分之研究

碩士 / 國立中山大學 / 海洋資源學系研究所 / 89 / The methylene chloride and acetone extracts of Formosan soft coral Clavularia violacea (Collected at Green Island) were found to exhibit significant cytotoxicity against P-388, A-549 and HT-29 cancer cell lines. Chromatographic separation let to the isolation of one prostanoid, 1, two cembranoid deterpenes, 2 and 3, one aromadedrane-type sesquiterpene, 4, one neodollabellane diterpene, 5, (+)-curcuphenol, 6 and two sesquiterpene lactones, 7 and 8. Compounds 1, 2, 4, and were new compounds. Compounds 1-5 exhibited significant cytotoxicity against P-388, HT-29 and A-549 cancer cell.

Identiferoai:union.ndltd.org:TW/089NSYS5277011
Date January 2001
CreatorsChih-Ju Chu, 朱芝茹
ContributorsChang-Yi Du, 杜昌益
Source SetsNational Digital Library of Theses and Dissertations in Taiwan
Languagezh-TW
Detected LanguageEnglish
Type學位論文 ; thesis
Format95

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