碩士 / 台北醫學院 / 保健營養學研究所 / 89 / The proposed study is to evaluate the etiology of major depressive disorder especially in dietary pattern, and the effectiveness of fish oil supplementation on clinical improvement. Eighteen major depressive disorder patients were recruited from Department of psychiatry, Taipei Medical University Municipal Wan Fang Hospital, aged from 18 to 65 years. A total of 19 age-sex matched healthy community controls were recruited as controlled subjects. The food frequency questionnaire, twenty four-hour dietary recall and three-day dietary record were used to investigate the differences of nutrients intake between major depressive disorder patients and normal individuals. In dietary frequency questionnaire, the results indicated the dietary pattern of major depressive patients is similar to the normal individual except the drinking milk. According to the three dietary record, the intake of cholesterol, linoleic acid, linolenic acid, niacin, ash and sodium (fresh food) in major depressive patients was significantly less than of normal adults. To compare the dietary nutrients intake, the data from three-day dietary record is more reliable than twenty four-hour dietary recall. The other factors such as age, sex, body mass index and intake of other nutrients showed no significant differences between major depressive disorder patients and normal subjects. Furthermore, the n-3 fatty acids supplementation (4.4 g EPA and 2.2 g DHA) in major depressive patients is significantly improved in HRSD score in 6th week.
| Identifer | oai:union.ndltd.org:TW/089TMC00217012 |
| Date | January 2001 |
| Creators | Chin-Hua Liu, 劉金華 |
| Contributors | Ming-Jer Shieh, Shih-Yi Huang, 謝明哲, 黃士懿 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 151 |
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