碩士 / 高雄醫學大學 / 心理學研究所碩士班 / 95 / Objective：Vecchi et al. (1999) proposed the amount of active processing could detect the variation of working memory in patients with Mild Dementia of Alzheimer’s Type (MDAT). Active processing refers to the modification, integration, or transformation of information which may be required by a task. This research was designed to investigate the level of cognitive deficit in patients with Very Mild Dementia of Alzheimer’s Type (VMDAT), by comparing the performance between healthy elderly and patients with dementia in distinct stage in active processing task. It was expected that the exploration of this research could be regarded as a basis of clinical diagnosis and treatment.
Methods：Participants include 29 patients with MDAT, 31 patients with VMDAT, and 32 healthy elderly. A variety of verbal and nonverbal active processing tasks were performed, include Logical Memory of Wechsler Memory Scale-III (WMS-III), Zing’s scale of verbal working memory, Scale of instrumental verbal working memory of daily life, Comprehensive Non-verbal Memory Test Battery (CNMT), Fuld Object Memory Evaluation (FOME).
Results：Comparing to patients with MDAT, healthy elderly performed better in all index. Healthy elderly performed more superior to patients with VMDAT in all index except for ineffective reminders and retention of FOME. Patients with VMDAT were doing better than patients with MDAT at Logical Memory of WMS-III, all index of FOME, CL of CNMT. More healthy elderly achieve learning stage in CNMT than patients with VMDAT.
Conclusion：The results suggested that verbal and nonverbal active processing were impaired in patients with VMDAT. Patients with VMDAT performed better than patients with MDAT while verbal information accompany with logical concept. The stability and executive function in learning nonverbal information was impaired in patients with VMDAT and MDAT. Patients with MDAT were also performed worse than patients with VMDAT on some component of learning ability. It concluded that the deterioration of working memory component in patients with VMDAT was significant different from healthy elderly and patients with MDAT. The exploration were be used to design a test battery for screening patients with VMDAT, and a cognitive rehabilitation program for training patients with VMDAT.
| Identifer | oai:union.ndltd.org:TW/095KMC05071003 |
| Date | January 2007 |
| Creators | Hsiao-Ting Ho, 何曉婷 |
| Contributors | Nai-Wen Guo, 郭乃文 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 181 |
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