碩士 / 國立成功大學 / 行為醫學研究所 / 95 / Literature regarding whether the early demented patients with Alzheimer’s disease (AD) have deficits in the feeling of knowing (FOK) function of episodic memory is scanty, and issues of whether these patients evidence executive dysfunction and of the underlying neuropsychological mechanism for FOK function have been controversial. The present study was explored these issues in questionably and mildly demented patients with AD. A total of 90 adult participants including, 30 questionably and 30 mildly demented patients with AD, and 30 normal healthy controls matched for the sex, age, and education level participated in this study. All subjects received a RJR paradigm task and a battery of neuropsychological tests, mainly including memory and executive function measures. The results revealed that both questionably and mildly demented patients’ performance on the FOK judgment task was significantly poorer than that of normal control counterparts, and these demented patients evidenced deficits of executive function other than memory impairment. Most of the demented patients with defective function of FOK also manifested impairments of memory and executive function. These results partially confirm findings evident in the literature, and we further suggest that deficits of both memory and executive function might account for the impairment of FOK in our demented patients. Nonetheless, since majority of our current aging people including demented ones in Taiwan are low-educated, the verbal FOK task used in this study might not be adequate for them. Further investigation on this issue in these low-educated demented patients is necessary.
| Identifer | oai:union.ndltd.org:TW/095NCKU5666001 |
| Date | January 2006 |
| Creators | Ya-Ling Wang, 王雅齡 |
| Contributors | Mau-Sun Hua, Huei-Chen Ko, 花茂棽, 柯慧貞 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 79 |
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