Evaluation of alginate-polyglutamic acid hydrogel for wound dressing / 海藻酸-聚麩胺酸水膠應用於創傷敷料之評估

碩士 / 國立臺灣科技大學 / 高分子系 / 95 / In this study, we successfully used calcium form γ-polyglutamic acid to prepare a novel alginate hydrogel instead of traditional process that used calcium chloride to perform ion crosslinking. The resulting hydrogels were characterized using FTIR spectroscopy, basic swelling behavior test, and the stability in a phosphate solution. Water resistance tests, water vapor transmission test, and other biocompatible tests were performed to evaluate the applicability of this hydrogel as a wound dressing material. The results show that this hydrogel exhibits pH-sensitivity, higher platelet adhering ability, and shorter coagulation time. Overall results demonstrated the alginate-polyglutamic acid hydrgel have a potential for wound dressing and drug delivery regions.

Identiferoai:union.ndltd.org:TW/095NTUS5310026
Date January 2007
CreatorsFang-jing Sheu, 許芳菁
ContributorsMing-chien Yang, 楊銘乾
Source SetsNational Digital Library of Theses and Dissertations in Taiwan
Languagezh-TW
Detected LanguageEnglish
Type學位論文 ; thesis
Format71

Page generated in 0.0015 seconds