Study of Alginate Hydrogel Crosslinked with γ-Polyglutamic Acid and Blended with Temperature-Responsive Pluronic F127 / 以γ-聚麩胺酸交聯海藻酸並利用感溫性F127改良水膠性質之探討

碩士 / 國立臺灣科技大學 / 高分子系 / 95 / In this study, the improved mechanical properties, swelling behavior and affect of blood-compatibility was investigated by an novel of hydrogels synthesized technique by cross-linking calcium poly(γ-glutamic acid) (γ-PGA) and alginate sodium with blended of various ratios nonionic surfactant Pluronic F127 with temperaturesensitive.
Results showed that the addition of Pluronic F127 can not only improve mechanical properties efficiently but also influence the temperature- sensitive swelling of hydrogels, it also exerted minor effect on the pH-sensitive swelling and promote anticoagulation.
As to an dream of biomaterials should have good biocompatibility, blood-compatibility, biodegradability and outstanding mechanical properties, this research can say that succeed in being close to the predeterminated target.

Identiferoai:union.ndltd.org:TW/095NTUS5310030
Date January 2007
CreatorsChai-Wei Kuo, 郭家維
ContributorsMing-Chien Yang, 楊銘乾
Source SetsNational Digital Library of Theses and Dissertations in Taiwan
Languagezh-TW
Detected LanguageEnglish
Type學位論文 ; thesis
Format89

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