博士 / 國立中正大學 / 心理學所 / 96 / Granular and pyramidal cells in hippocampus are continually born after postnatal period. Past research has mostly focused on the effects of contextual fear conditioning (CFC) on granular cells of hippocampal neurogenesis. The present study attempted to investigate the effects of CFC on the numbers of hippocampal granular and pyramidal neurons in rats before and after puberty, as well as a comparison of CFC and light fear conditioning (LFC) on the neurogenesis. Experiment 1 found that CFC increases the numbers of both the granular and pyramidal cells in 10 weeks-old rats. In the Experiment 2, rats before puberty (4 to 6 weeks) and after puberty (8 to 12 weeks) were undergone a CFC procedure and compared on the proliferation of their granular and pyramidal cells. Results suggested that CFC improved the proliferation of both granular and pyramidal cells. Experiment 3 investigated the effects of CFC and LFC on rats before and after puberty. Findings suggested that under these two conditionings, the number of the granular cell increased. The numbers of granular and pyramidal cells were more in CFC than in LFC. Furthermore, LFC had a significant effect on the pyramidal cells of rats after puberty. Taken together, the present study suggested that CFC increases proliferation on both the granular and pyramidal cells of rats and LFC would have effects on the pyramidal cells of rats after puberty. These results have further our understanding on the influence of fear conditioning on the hippocampal neurogenesis.
| Identifer | oai:union.ndltd.org:TW/096CCU05071013 |
| Date | January 2008 |
| Creators | Puppy Chen-Huang, 柯政宏 |
| Contributors | none, 黃世琤 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 73 |
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