Studies on the Chemical Constituents of Houttuynia cordata Thunb. and Humulus scandens (Lour.) Merr. / 魚腥草與葎草之化學成分研究

碩士 / 中國醫藥大學 / 藥物化學研究所 / 96 / 第一部份 魚腥草之化學成分研究
In the present investigation, the whole plant of Houttuynia cordata Thunb. was collected and extracted with methanol. The extracts were further separated by column chromatography and high performance liquid chromatography. Ten compounds were isolated, and they contain two aristolactams: aristolactam BⅡ(2) and aristolactam AⅡ(5); one oxoap- orphine: splendidine (10); three 4,5-dioxoaporphines: cepharadione B (1), piperadione (3) and norcepharadione B (4); two flavonoids: quercitrin (6) and quercetin-3-O-β-D-galactoside (7); one benzenoid: caffeic acid (8); one amide: benzamide (9)。
These compounds were characterized by comprehensive analysis of their 1D and 2D NMR and mass spectra. Among them, piperadione (3) and caffeic acid (8) are isolated from Houttuynia cordata for the first time.

第二部份 葎草之化學成分研究
In the present investigation, the whole plant of Humulus scan- dens (Lour.) Merr. was collected and extracted with methanol. The extracts were further separated by column chromatography and high performance liquid chromatography. Five compounds: β-stiosteryl-3-O-β-D-glucoside (a), sucrose (b), myo-inositol (c), 3-hydroxy-4,4-dimethyl-4-butyrolactone (d), 2,3-dihydroxy-2- methylbutyrolactone (e) were isolated from Humulus scandens (Lour.) Merr.
The structural elucidation of the isolated natural products were established by spectral methods.

Identiferoai:union.ndltd.org:TW/096CMCH5549006
Date January 2008
CreatorsPei-Ru Huang, 黃珮茹
Contributors廖志中
Source SetsNational Digital Library of Theses and Dissertations in Taiwan
Languagezh-TW
Detected LanguageEnglish
Type學位論文 ; thesis
Format202

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