碩士 / 國立交通大學 / 環境工程系所 / 96 / The objective of this study is to study the toxic effect of primary propargylic alcohols on Pseudokirchneriella subcapitata using a closed system test. The effects of primary propargylic acids were evaluated by three kinds of response endpoints, i.e., dissolved oxygen production, cell density and algal growth rate. Median effective concentratons (EC50s) were estimated using the Probit model with a test duration of 48hr. Primary propargylic alcohols with alkene on the second position exhibit higher toxicity than alkene on the third position. The quantitative structure-activity relationships (QSARs) were established based on the 1-octanol/water partition coefficient (logKow) and using log(1/EC50) , 2-propyn-1-ol was not included , revealed a good regression relationship (R2=0.9, based on final yield).
The results also reveal that the value of the lower effect concentration of the primary propargylic alcohols (cell density, algal growth rate, and the dissolved oxygen production). This demonstrates that the NOEC value can offer a better standard for protecting our aquatic environment than the EC10 value . Hence, comparing with other aquatic organismsthe acute toxicity data , The order of the relative sensitivity is then obtained as follows : Fathead minnows> P. subcapitata > Tetrahymena pyriformis.
| Identifer | oai:union.ndltd.org:TW/096NCTU5515022 |
| Date | January 2008 |
| Creators | Kwan-Liang Kuo, 郭冠良 |
| Contributors | Chung-Yuan Chen, 陳重元 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 123 |
Page generated in 0.0018 seconds