碩士 / 國立臺灣海洋大學 / 食品科學系 / 96 / Astaxanthin (3,3’-dihydroxy-β-β’-carotene-4-4’-dione) has been gaining widespread popularity as a dietary supplement due to its powerful antioxidant properties. Similar to other carotenoids, astaxanthin is a highly unsaturated molecule and thus, can easily be degraded by thermal or oxidative processes during the manufacture and storage of foods. This may cause the loss of their nutritive and desirable biological properties.
Cyclodextrins (CDs) are composed of α-1,4-linked glucopyranose subunits, these apolar internal cavities can form complexes with and solubilize many normally water-insoluble compounds.
The synthesised chitosan/β-cyclodextrin polymer exhibits the characteristics of a possible drug delivery system with some inclusion properties from β-cyclodextrin. β-cyclodextrin was successfully grafted onto a chitosan chain polymer with a cyclodextrin grafting yield of 7 %.
The astaxanthin microemulsion with 95 wt % aqueous phase with added 0.05 % chitosan/β-cyclodextrin has the highest astaxanthin solubility. For the astaxanthin microemulsion with 40 wt % aqueous phase, the group with added chitosan/β-cyclodextrin has the highest efficacy of scavenging ABTS+. The flow behavior of astaxanthin microemulsion is a Newtonian fluid.
The astaxanthin microemulsion makes good absorbance at UVC zone (280-200 nm). The astaxanthin microemulsion of 40 wt % aqueous phase is more stable than the group with added the carriers under UV radiation. The 40 wt % aqueous phase composition makes astaxanthin more stable than T64 and the group with added the carriers provides more thermal protection for astaxanthin.
The astaxanthin microemulsion with added chitosan/β-cyclodextrin has the potential to increase the solubility of astaxanthin and provides more protection for astaxanthin.
| Identifer | oai:union.ndltd.org:TW/096NTOU5253015 |
| Date | January 2008 |
| Creators | Shih-Pin Huang, 黃士繽 |
| Contributors | Ke-Liang B. Chang, 張克亮 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 89 |
Page generated in 0.3117 seconds