碩士 / 國立嘉義大學 / 水生生物科學系研究所 / 97 / Fates of Nitrofurans and Degradation Intermediate Products in Aquaculture Pond Waters and Sediments
Abstract
Nitrofurans (NFs) were applied in aquaculture previously on treatment of infections caused by bacteria, but the low bioavailability and the half-lives (t1/2) short change fast into of nitrofuran metabolite (NFMs) in aquaculture animals. Therefore, these were non-utilized drugs which enter and remaim in water environment. This research include four NFs of furaltadone (FTD), furazolidone (FZD), nitrofurantoin and nitrofurazone. Nitrofuran degradation intermediate products (NFDIs) were 3-amino-5-morpholinomethyl-2-oxazolidinone (AOZ), 3-amino-2-oxazoli-
dinone (AOZ), 1-aminohydantoin hydrochloride (AH）and semicarbazide hydrochloride (SC）. In order to distinguish NFs and NFDIs were maybe changed and fated in aquaculture pond waters and sediment slurries. Hence, this purpose of study that probe the effects of light (Light and dark), microbial activities (non-sterile and sterile) and temperatures (10, 25 and 40℃) on the degradation of these four NFs and NFDIs in aquaculture pond waters and sediment slurries were investigated. Moreover, four NFs the degradation products for fours metabolites in aquaculture pond waters and sediment slurries.
The experimental result shows that all four NFs in aquaculture pond waters and sediment slurries with treament natural light conditions for t1/2 shown 0.06 – 0.09 days and 1.62 – 3.17 days were significant degraded faster than which in the dark (t1/2, 6.11 – 25.27 and 2.46 – 22.33 days). Similarly, four NFDIs were significant degraded faster in aquaculture pond waters and sediment slurries with treament natural light conditions (t1/2, 0.27 – 0.79 and 5.30 – 13.91 days) than in the dark (t1/2, 11.76 – 486.92 days and 11.74 – 205.32 days), too.
The microbial activity condition was on the degradation of four NFs and NFDIs in aquaculture pond waters and sediment slurries. In temperature part, the increased degradation of NFs and NFDIs followed the increased of temperature.The degradation products determined were AMOZ, AOZ, AH, SC for FTD, FZD, NFT, NFZ, respectively. During the 100-d experiment, concentrations of the degradation products for added NFs (5 mg/L) reached 1.87 – 2.99 mg/L and 1.77 – 2.50 mg/L. At end of the experiment, there were still 0.02 – 0.73 mg/L of NFs remained (about 0.4% – 14.6% of the initial addition).
Keywords: nitrofurans, degradation, light, microbial, temperatures.
| Identifer | oai:union.ndltd.org:TW/097NCYU5061004 |
| Date | January 2009 |
| Creators | Wen-Hui Yu, 余雯惠 |
| Contributors | Hong-Thih Lai, Ph. D., Tzong-Shean Chin, Ph. D., 賴弘智, 秦宗顯 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 177 |
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