碩士 / 國立東華大學 / 海洋生物多樣性及演化研究所 / 97 / Polybrominated diphenyl ethers (PBDEs) are a group of emerging persistent organic pollutants (POPs) widely used as brominated flame retardants. Among the 209 possible congeners, PBDE-47 is the most common PBDE congener found in biological samples. Recent studies have shown that PBDEs may cause toxic effects to interfere with endocrine systems and reproduction, or to neurobehavioral damages in animals. However, related research on fish is scarce. In this study we chose zebrafish as the model species. Zebrafish were fed food dosed with PBDE-47 (control, solvent control, 10, 100 and 1000 ng/g) from 21 days post hatch (dph). Fish length, weigh and morphology were recorded at 38 and 90 dph, and their swimming behavior was assessed at 54 dph. All samples were fixed for whole fish histological analysis after the end of PBDE-47 exposure at 90 dph. There was no significant difference within five treatments both on length and weight each at 38 and 90 dph. In the behavioral analysis, there was no significant difference on maximum swimming speed. However, both total swimming distance and percent time active were significantly decreased in 1000 ng/g group than that in control. Histological analysis showed that PBDE-47 exposure caused no significant effect on gonad development in both male and female fish. In summary, this study showed that chronic dietary PBDE-47 exposure did not affect growth or gonad development but caused negative effect on swimming performance of zebrafish.
| Identifer | oai:union.ndltd.org:TW/097NDHU5270024 |
| Date | January 2009 |
| Creators | Chun-Ting Chou, 周俊廷 |
| Contributors | Te-Hao Chen, 陳德豪 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 59 |
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