碩士 / 國立東華大學 / 海洋生物科技研究所 / 98 / Studying on chemical constituents of Chondria ryukyuensis Yamada collected off the coast of southern Taiwan. The methol extract of Chondria ryukyuensis have resulted in isolation of two steroid compounds, a new compound 6, 15-dihydroxy-cholest-4-ene-3-one (1) and a known compound Cholest-4-ene-3,6-dione (2) and seven β-carboline compounds, including three known compounds, 1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid (3)、methyl 1, 2, 3, 4-tetrahydro -β-carboline-3-carboxylate (4)and ethyl 1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylate (5), along with four new compounds, methyl 2-(4- hydroxybenzyl)-1, 2, 3, 4-tetrahydro-β-carboline -3-carboxylate (6)、ethyl 2-(4-hydroxybenzyl)-1, 2, 3, 4-tetrahydro-β- carboline-3-carboxylate (7)、4-hydroxybenzyl 2-(4-hydroxybenzyl)-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylate (8)和CR-9 (9) The structures of compounds 1-9 were determined by spectroscopic methods. In the biological activity testing, complound 2 only displayed strong cytotoxicity against CCRF-CEM and DLD-1 cells.
| Identifer | oai:union.ndltd.org:TW/098NDHU5270025 |
| Date | January 1900 |
| Creators | Chih-Yu Chen, 陳致宇 |
| Contributors | Chung-Kuang Lu, Ping-Jyun Sung, 盧重光, 宋秉鈞 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 175 |
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