碩士 / 國立中興大學 / 食品暨應用生物科技學系所 / 99 / Oral strip is an extended application from edible film and can be added with various kinds of active pharmaceutical ingredients depending on the consumer''s need. The aim of this study was to develop a tapioca starch/sodium alginate based oral strip protocol with lemongrass essential oil (LEO). The thickness, gloss, mechanical property, solubility, microstructure and the deodorizing activity of the oral strip protocol would be evaluated as well. Composition analysis of LEO revealed that the major component in LEO was beta - citral. Physical properties of film-forming solutions with different starch/alginate ratios to make a total solid content of 3%, and added with 0.6% glycerol and 0.25% lemongrass essential oil (LEO), were then evaluated. It was found that the final viscosity of film forming solution increased with increasing the ratio of sodium alginate, and samples with a starch/sodium alginate ratio of 2.2/0.8 showed the highest final viscosity (up to 581 mPa‧s). The gloss appearance, moisture content and water solubility of the resulting oral strip was about 100, 13% and 67%, respectively. Mechanical characteristics, including puncture and tensile strength, were about 9 and 40 N, respectively. As starch/alginate ratio was maintained at 2.2/0.8 but adding different concentrations of LEO, the mechanical strength of oral strip decreased with increasing LEO concentrations, implying the plasticizer-like effect of LEO. Antibacterial test results revealed that the inhibition diameter of oral pathogen (Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Fusobacterium nucleatum) increased with increasing LEO concentration, particularly 1% LEO showed the most pronounced inhibition on Porphyromonas gingivalis and Prevotella intermedia. Furthermore, oral strip incorporated with 1% LEO showed significant inhibition on Prevotella intermedia. However, model deodorizing test results revealed that oral strip with various concentrations of LEO did not show significant effect on scavenging diallyl sulfide and diallyl disulfide. Hedonic sensory evaluation of oral strips incorporated with different concentrations of LEO was further performed by 35 panelists. The acceptable LEO level in starch/alginate based oral strip was found to be 0 - 0.5%. These results implied that starch/alginate based oral strip with LEO had application potential as a deodorizing product, and deserved for further research works.
| Identifer | oai:union.ndltd.org:TW/099NCHU5253018 |
| Date | January 2011 |
| Creators | Jian-Hong Chen, 陳建宏 |
| Contributors | 賴麗旭 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 122 |
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