碩士 / 國立臺灣海洋大學 / 食品科學系 / 99 / Palytoxin is one of the most potent marine toxic compound with non-protein structure, and it causes food poisoning cases by food-chain accumulation.
In Pacific area, trunkfish is one kind of food. Especially in Japan, many palytoxin-like food poisoning cases occurred by ingestion of trunkfish. It also occurred once in Taiwan; however, palytoxin was not identified in this case until now. In this study, we first studied on palytoxin-like toxicity from family Ostraciidae fish in Taiwan by hemolysis activity and mouse bioassay. The fish seem to contain palytoxin-like compounds. In aged trunkfish, the toxicity in liver tissue is more toxic than that in muscle, but it is opposite in smaller trunkfish.
In Taiwan, toxic dinoflagelate Ostreopsis spp. And soft coral Palythoa spp. are the main resources of palytoxin. But the toxin profiles of palytoxin in Taiwan is still lack. In the second part, we used hemolysis activity of palytoxin to investigate palytoxin stability under different ion, acid and alkali conditions. The results showed that hemolysis activity of palytoxin was significantly reduced when treated with Cu2+ and acetic acid (pH 3). Fe3+, Fe2+ and Zn2+ would slightly inhibit the hemolysis activity of palytoxin. Hydrogen chloride, sodium hydroxide and sodium carbonate would not change the hemolysis activity of palytoxin.
| Identifer | oai:union.ndltd.org:TW/099NTOU5253058 |
| Date | January 2011 |
| Creators | Shih-Ting Lin, 林詩婷 |
| Contributors | Deng-Fwu Hwang, 黃登福 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 92 |
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