碩士 / 國立交通大學 / 環境工程系所 / 100 / A single-cell green algae (Pseudokirchneriella subcapitata) for the toxicity testing species to α,β-unsaturated carbonyl compounds as a test toxic in three reaction endpoints (ΔDO, Final Yield, Growth Rate) on closed system for toxicity testing.
The results of QSAR in three reaction endpoints : Log (1/EC50) = 0.965 + 0.968 Log(1/RC50) +0.169 LogKOW r2=0.806 (Δ DO), Log (1/EC50) = 1.200 + 1.000 Log(1/RC50) + 0.113 LogKOW r2=0.832 (Final Yield), Log(1/ EC50) = 0.985 + 0.997 Log(1/RC50) + 0.075 LogKOW r2=0.854(Growth Rate).
The QSAR of α,β-unsaturated carbonyl compounds not only predict other a,b-unsaturated carbonyl compounds which untested but also provide tools capable of the rapid screening of chemicals for potential hazards.
Most α,β-unsaturated carbonyl compounds are more than 1, that the toxicity of the reactive compounds are more intense than baseline toxicity. Algae toxicity data on Pseudokirchneriella subcapitata of α,β-unsaturated carbonyl compounds make more complete to toxicity datas of reactive organic chemicals.
Keywords: α,β-unsaturated aldehydes, Pseudokirchneriella subcapitata, QSAR, reactive organic
| Identifer | oai:union.ndltd.org:TW/100NCTU5515002 |
| Date | January 2011 |
| Creators | Lin, Sz-Hung, 林思宏 |
| Contributors | Chen, Chung-Yuan, 陳重元 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 119 |
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