Relationship between Methadone Therapy and Heroin Relapse — a Case Study on Heroin Users in Northern Taiwan / 接受美沙冬療法者再使用海洛因行為之相關因素研究--以臺灣北區海洛因使用者為例

碩士 / 國立臺灣師範大學 / 健康促進與衛生教育學系在職進修碩士班 / 100 / The purpose of this thesis is to understand the condition and correlation between the socio-demographic variables, clinical physiological variables, knowledge of methadone therapy, intensity of heroin craving, and heroin relapse for four heroin users undertaking methadone therapy in Northern Taiwan. This study uses secondary data that have been collected since 2008. Five hundred ninety-nine case studies were selected through a purposive sampling approach. The necessary data was acquired using semi-structured questionnaires, which were filled out during one-on-one interviews conducted by methadone case managers. Clinical case data was obtained from out-patient department systems. The acquired data were processed and analyzed using descriptive statistics, the chi-square, and the .2-series of the related and binary logistic regression. The results of this study are summarized as follows:

1.The majority of participants in this study are men (87.0%), have a junior high school education level (50.2%), are aged between 31 and 40 y (41.7%), and first used heroin when they were aged between 21 and 30 y (45.7%). Among the participants of this study, 71 (12.4%) are HIV positive, 514 (93.1%) are hepatitis C positive, and 382 (67.4%) tested positive for morphine in the urine screening test. The average methadone dosage of participants was 38.88 mg/d during the period of this study.
2.Regarding the participants’ knowledge of methadone, the overall ratio of correct replies on methadone knowledge items is high, indicating that the majority of participants’ methadone knowledge is correct.
3.The answer distribution from the majority of participants on the various dimensions of craving measurement questions is “agree.” This indicates that the participants’ cravings for heroin are moderate-to-high, and that they continue to crave heroin even after rehabilitation with methadone.
4.Participants’ methadone knowledge and craving attitude are positively correlated, indicating that participants scoring higher on methadone knowledge also score higher on craving attitude.
5.Among the participants in this study, 65.4% (242) have discontinued using heroin, whereas 34.6% (128) have relapsed.
6.There is no significant difference between HIV screening results and heroin relapse behavior. There is a significant difference between Hepatitis C screening results and heroin relapse behavior.
7.The results of logistic regression analysis on heroin relapse behavior showed that the statistically significant variables are “the most recent hepatitis C examination result,” “age,” “age of first heroin use,” “most recent methadone dosage,” and “craving attitude — compulsive behavior.”

Identiferoai:union.ndltd.org:TW/100NTNU5571075
Date January 2011
CreatorsPei-Chin Wang, 王佩瑾
ContributorsTony Szu-Hsien Lee, 李思賢
Source SetsNational Digital Library of Theses and Dissertations in Taiwan
Languagezh-TW
Detected LanguageEnglish
Type學位論文 ; thesis
Format134

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