碩士 / 弘光科技大學 / 化妝品科技研究所 / 104 / According to cell experiments and animal experiments, Fucoidan has an outstanding performance in anti-inflammation, anti-tumor and anti-cancer. The experiments also pointed out Fucoidan’s hyperplasia effect on fibroblast growth. In this study, the author moved one step further to investigate small molecular Fucoidan cream’s performance in anti-aging.
The author prepared three creams containing 1.00%, 3.00%, and 10.00% of small molecular Fucoidan respectively for anti-bacterial test, stability test and human subject research. According to the test redness, the subject’s derma redness was improved by 7.34% (*p<0.05) and their derma collagen structure was improved by 24.99% (*p<0.05) after they used the cream containing 1.00% of small molecular Fucoidan for 14 days, the subjects’ derma Texture was 32.10% improved (*p<0.05) and the derma pores were 37.18% improved (*p<0.05) after they used the cream containing 3.00% of small molecular Fucoidan for 7 days, the subjects’ derma collagen structure was 21.82% improved (*p<0.05) after they used the cream containing 10.00% of small molecular Fucoidan for 7 days. The author went on to investigate the effects produced by the creams containing different percentages of small molecular Fucoidan cream for users of different age groups. The experiments indicated a significant effect on derma collagen structure after users in the age group 54~60 used the cream containing 10.00% of small molecular Fucoidan, a significant effect on derma Texture after users in the age group 40~50 used the cream containing 3.00% of small molecular Fucoidan, and an increase of the derma pores after users in the age group 30~39 used the cream containing 1.00% of small molecular Fucoidan.
In summary, the subject’s derma Texture, pores, Spots, elasticity, derma melanin, derma redness, derma collagen structure and pigmentation- redness had been improved significantly after they used three creams containing 1.00%, 3.00% and 10.00% of small molecular Fucoidan respectively for either 7 days or 14 days. The results proved small molecular Fucoidan cream’s effect on anti-aging.
| Identifer | oai:union.ndltd.org:TW/104HKU00793011 |
| Date | January 2016 |
| Creators | Wu,Cian-Yi, 吳芊逸 |
| Contributors | Yih,Kuang-Hway, 易光輝 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 109 |
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