碩士 / 國立成功大學 / 環境工程學系 / 104 / Many kinds of endocrine disrupting chemicals (EDCs) have been used in our daily lives. EDCs are able to interfere with the endocrine system, thus probably cause adverse effects on the organisms. In this study, recombinant yeast bioassays were used to detect androgen receptor (AR), estrogen receptor (ER) and mineralocorticoid receptor (MR) disrupting activities in sediment samples from Taiwanese rivers and Kaohsiung Harbor. In addition, sediment samples were also analyzed by gas and liquid chromatography mass spectrometry (GC/MS, LC-MS/MS) to quantify the concentrations of target polycyclic aromatic hydrocarbons (PAHs), polybrominated diphenyl ethers (PBDEs) and EDCs. Bioassay results revealed that AR, MR, ER antagonist activities were detected in sediment samples, whereas no agonist activity was found. Instrumental analysis showed that the most often detected compounds were 2-4 rings PAHs, decaBDE, bisphenol A, nonylphenol, triclosan, and triclocarban. However, they were not the leading contributors to the AR, MR, and ER antagonist potencies observed in the river sediment samples. Compared to other studies, PAH concentrations in the harbor sediments were generally higher than river sediments. In future work, we will try to identify the unknown endocrine disruptors in sediment samples
| Identifer | oai:union.ndltd.org:TW/104NCKU5515153 |
| Date | January 2016 |
| Creators | Jin-TingChen, 陳勁廷 |
| Contributors | Pei-Hsin Chou, 周佩欣 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 128 |
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