碩士 / 國立臺北科技大學 / 化學工程研究所 / 104 / 3D printing technology produces scaffolds with interconnected pores. They facilitate cell growth, nutrient and metabolic waste transportation. Electro spun method produces nanofibers with large surface area and pore structure, mimicking the extracellular matrix. Combing 3D printing technology and electro spun technology to manufacture skin dressing composites. Electro spun material selection chitosan and polyvinyl alcohol are all biodegradable material, and use concentrated acetic acid (90 vol %) as a solvent. It can effectively reduce the surface tension，increase the charge density, form nanofibers. Improving mechanical properties by glutaraldehyde vapor cross-linked nanofibers as the skin surface. 3D printing material choice alginate hydrogel with calcium chloride crosslinked to form gelled as the dermal layer. And finally bonding two kinds of product biological with glue to form composite.
Compared composites material with 3D molded alginate hydrogel scaffold, composites material scaffolds have a higher tensile strength, low degradation rate, swelling rate and water vapor permeability.
Composites material value slightly above but below lidless container moisture permeability values. It also has good growth on the biocompatibility.
| Identifer | oai:union.ndltd.org:TW/104TIT05063097 |
| Date | January 2016 |
| Creators | HUEI-SYUAN,LIN, 林慧宣 |
| Contributors | Hsin-Yi Lin, 林忻怡 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 0 |
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