碩士 / 中華科技大學 / 健康科技研究所在職專班 / 105 / Aloin has long been used for medicines, food products and cosmetic purposes, because it also exhibits wound healing, antimicrobial, anti-inflammatory, anti- oxidant, anti-radiation, antimicrobial, anti-cancer and anti-tumor activities. This study attempted to develop sodium alginate/pectin hydrogels containing aloin for potential applications as wound dressing. Calcium chloride was used to crosslink the sodium alginate/pectin hydrogels in order to reinforce their structure. The swelling behavior of the prepared hydrogels was examined with a pH ranging from 4 to 10 which exhibited increased swelling ratio with increaseing pH values. The total phenolic content and antioxidant activity of sodium alginate/pectin-aloin hydrogels were evaluated using the Folin-Ciocalteau method, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity and ferrous ion chelating ability assays. In vitro indirect MTT assay also showed that the sodium alginate/pectin-aloin hydrogels have good cytocompatibility to L929 mouse fibroblasts. The results suggest that sodium alginate/pectin-aloin hydrogels loaded with aloin can be used as wound dressing.
| Identifer | oai:union.ndltd.org:TW/105CHIT1743003 |
| Date | January 2017 |
| Creators | YEN, MING-ING, 顏明英 |
| Contributors | JAO, WIN-CHUN, 饒文娟 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 60 |
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