碩士 / 中原大學 / 化學工程研究所 / 107 / In this study, the oil phase encapsulated hydrophilic Albumin （aqueous phase） was prepared by emulsification to form a W/O （water in oil） emulsion. An aqueous solution of sodium alginate was added to form a W/O/W emulsion, in order to cure emulsion into microcapsules.We used the sodium alginate to make the outer layer colloid. Dripping albumin-encapsulated emulsion in calcium chloride solution. Cured emulsion into microcapsules by an ionic gelation method.
The purpose of this experimental microencapsulation is to protect albumin from external environmental factors, delay the decline of albumin antioxidant activity, and achieve the function of effectively encapsulating albumin.
In this study, we used different concentrations of sodium alginate and calcium chloride aqueous solution as parameters to conduct the experiments, and then discussed the encapsulation efficiency and release rate of albumin microcapsules.
We need to manufacture microcapsules with high encapsulation efficiency and to stable the encapsulation of albumin.The two best results are microcapsules made with a conditional sodium alginate concentration of 3.0 wt% and a calcium chloride concentration of 10.0 wt%. It has the highest encapsulation efficiency of 92.53% and the lowest average release rate of 14.97%. The Iron-chelating ability test showed that albumin in the microcapsule antioxidant activity was increased with days, which means that the microcapsules did have the anti-oxidation ability and slow release ability of albumin.
| Identifer | oai:union.ndltd.org:TW/107CYCU5063008 |
| Date | January 2019 |
| Creators | Tzu-Yin Hsieh, 謝紫音 |
| Contributors | Tsair-Wang Chung, 鍾財王 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 107 |
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