碩士 / 國立中央大學 / 化學工程與材料工程學系 / 107 / Abstract
In this study, several inorganic materials were chosen for the encapsulation of astaxanthin. The materials included activated carbon, phosphate, SBA-15, MCM-41 and aerosil. All of them are hydrophobic and porous, except silica. The hydrophobic property makes the materials easier to absorb the astaxanthin molecular. It is the major factor to choose them as the encapsulation agent. The porosity of the material affects the amount of astaxanthin absorbed by materials and encapsulation rate. Based on the absorption performance, one can decide whether the material can be applied to practical use or not. In this experiment, the astaxanthin composite powder was prepared and astaxanthin was encapsulated in the porous material. Astaxanthin in composite powder should be able to be released in human body. Hydrochloric acid solution with a trace of salt at pH value 1.4 and phosphate buffer solution with pH value 7.4 were used to simulate the performance of astaxanthin composite powder in stomach and small intestine. The dissolution results show that all kind of astaxanthin composite powder can release astaxanthin in human bodies and phosphate is the most efficient one. In this study, Ultraviolet–visible spectroscopy (UV/vis) was used to analyze the samples. The composite powder was dissolved in Dimethyl sulfoxide and analyzed with UV/vis spectrophotometer. The amount of astaxanthin in composite powder was obtained by the absorbance of samples and the encapsulation rate was calculated. The experimental results show that the silica we use is not suitable for astaxanthin encapsulation due to its weak capability to absorb astaxanthin. Its encapsulation rate was low. Phosphate, MCM-41 and SBA-15 showed good performance in astaxanthin absorption. The results demonstrated that phosphate is the best one to adsorb astaxanthin and release it in human bodies among all materials. It has great potential in the encapsulation of astaxanthin.
| Identifer | oai:union.ndltd.org:TW/107NCU05063014 |
| Date | January 2019 |
| Creators | Wei-Shao Lin, 林韋劭 |
| Contributors | Yu-Wen Chen, 陳郁文 |
| Source Sets | National Digital Library of Theses and Dissertations in Taiwan |
| Language | zh-TW |
| Detected Language | English |
| Type | 學位論文 ; thesis |
| Format | 100 |
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