Ionomycin is a stereochemically complex calcium ionophore. An analogue (34) of ionomycin has been designed and its synthesis initiated. Regions of the analogue which parallel portions of ionomycin do not incorporate any of the chiral centers found in the natural product. The analogue 34 also incorporates a highly conserved tripeptide found in the calcium binding site of troponin C proteins.
[ Formula omitted ] / Science, Faculty of / Chemistry, Department of / Graduate
| Identifer | oai:union.ndltd.org:UBC/oai:circle.library.ubc.ca:2429/29761 |
| Date | January 1990 |
| Creators | Putland, Michael Stuart |
| Publisher | University of British Columbia |
| Source Sets | University of British Columbia |
| Language | English |
| Detected Language | English |
| Type | Text, Thesis/Dissertation |
| Rights | For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use. |
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