In this dissertation we present a new approach to estimate the volume of ischermic stroke lesions using magnetic resonance imagery (MRI). The approach is hierarchical, regularized, and guided by statistical theory, resulting in a confidence map for the lesion itself and a confidence interval for the lesion volume. We test the procedure on synthetic data and real MRI, with estimates to within 6% of the volumes from physicians' hand segmentations. These results compare favorably to those from other Bayesian-based methods. Also, we present a formulation of the free induction decay signal for several MR pulse sequences, which allow for the classification of distinct tissue types in MRI.
| Identifer | oai:union.ndltd.org:UMASS/oai:scholarworks.umass.edu:dissertations-3590 |
| Date | 01 January 2001 |
| Creators | Stein, Benjamin Reece |
| Publisher | ScholarWorks@UMass Amherst |
| Source Sets | University of Massachusetts, Amherst |
| Language | English |
| Detected Language | English |
| Type | text |
| Source | Doctoral Dissertations Available from Proquest |
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