Electrolytically generated copper and silver ions (400:40 and 800:80 μg/L) with and without chlorine (1 mg/L) were evaluated for their efficacy in reducing numbers of viable Naegleria fowleri amoebas in well water (23-25°C and pH 7.3). A 99.9% reduction was achieved by 10 minutes exposure to 1 mg/L free chlorine compared to 8 minutes with chlorine combined with copper:silver (800:80 μg/L). Copper:silver alone showed minimal reduction of N. fowleri after 72 hours exposure. Addition of 1 mg/L free chlorine to copper:silver at concentrations of 400:40 or 800:80 μg/L resulted in significantly enhanced inactivation rates (k = 0.4575 and 0.515 log₁₀ reduction/minute, respectively) than with chlorine alone (k = 0.33). Enhanced inactivation of N. fowleri with combined copper:silver and chlorine may be a consequence of multiple sites of attack on the amoeba membrane by the different disinfectants.
| Identifer | oai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/278172 |
| Date | January 1990 |
| Creators | Cassells, Janet Marie, 1957- |
| Contributors | Gerba, Charles P. |
| Publisher | The University of Arizona. |
| Source Sets | University of Arizona |
| Language | en_US |
| Detected Language | English |
| Type | text, Thesis-Reproduction (electronic) |
| Rights | Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. |
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