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Hodgkin Lymphoma Mimicking Osteomyelitis

Hodgkin lymphoma with symptomatic osseous involvement can have a similar presentation to osteomyelitis. Common findings in symptoms, laboratory workup, and imaging can make it very difficult to distinguish between the two diseases. Excisional biopsy should be pursued if fine-needle biopsy is equivocal and suspicion of lymphoma is high. We report a case of a 40-year-old man who presented with a history of marine animal sting on his neck and later developed erythema in the area, chest pain, constitutional symptoms, adenopathy, and imaging classic for sternal osteomyelitis. Fortunately, initial biopsy prompted the possibility of lymphoma, and further workup was initiated, which confirmed Hodgkin lymphoma. This case is a good reminder that malignancies and infections can share many common features, and keeping a broad differential diagnosis can be lifesaving. Proper staging and risk stratification of Hodgkin lymphoma help determine the optimal treatment. (C) 2017 The Author(s) Published by S. Karger AG, Basel

Identiferoai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/625840
Date20 June 2017
CreatorsMajeed, Aneela, Chan, Onyee, Okolo, Onyemaechi, Shponka, Volodymyr, Georgescu, Anca, Persky, Daniel
ContributorsUniv Arizona, Banner Univ, Med Ctr, Dept Infect Dis, Univ Arizona, Banner Univ, Med Ctr, Dept Med, Univ Arizona, Banner Univ, Med Ctr, Dept Pathol, Univ Arizona, Banner Univ, Med Ctr, Dept Hematol Oncol
PublisherKARGER
Source SetsUniversity of Arizona
LanguageEnglish
Detected LanguageEnglish
TypeArticle
Rights© 2017 The Author(s). This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).
Relationhttps://www.karger.com/?doi=10.1159/000474938

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