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Impact of a Smartphone-delivered Sedentary Behavior Intervention on Glucose Metabolism in Prediabetic Adults

A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine. / This study investigates whether an 8-week
lifestyle-based, smartphone-delivered intervention targeting reduction in sedentary behavior (i.e.,
sitting) significantly reduces objectively measured time spent sitting and improves fasting glucose
and insulin. The incidence of type II diabetes has continued to increase in the United States and
increases in sedentary behavior along with reductions in physical activity throughout the day have
contributed to the increase of disease. There were 31 participants in the study and they started
with a 3-week run-in period where a basic self- monitoring component was installed on their
smartphone. After this run-in period, participants were randomly assigned to one of the eight
experimental conditions. All participants received a basic self-monitoring with feedback component
where they self-reported sleep, sedentary, and more active behaviors. Sitting time was measured
with the activPAL3c, which is a device that they wore 24/7. Study visits occurred at week 0
(immediately after the 3-week run-in period), week 4, and week 8. Fasting glucose and insulin were
measured at each of these visits. Participants logged approximately 60% of their sleep, sedentary,
and exercise behaviors, which took 3– 4 min/day to complete. The impact of the intervention was not
significant, such that decreases in sedentary time in those assigned to the sedentary component did
not significantly differ from those not assigned to the sedentary component at 8 weeks (beta (SE)
= -1.19 (.32), p>0.05); however, the effect size was moderate (Cohen’s d = 0.29). There was no
significant
impact on fasting glucose or insulin.

Identiferoai:union.ndltd.org:arizona.edu/oai:arizona.openrepository.com:10150/626855
Date26 February 2018
CreatorsHicks, Meghan
ContributorsThe University of Arizona College of Medicine - Phoenix, Buman, Matthew MD
PublisherThe University of Arizona.
Source SetsUniversity of Arizona
Languageen_US
Detected LanguageEnglish
TypeThesis
RightsCopyright © is held by the author. Digital access to this material is made possible by the College of Medicine - Phoenix, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.

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