1-Aminoalkanephosphonic acids and their derivatives, have long been claimed to be compounds with a wide variety of application. Numerous examples exist where they have been described as: complex-forming agents with sequestrating properties, extractants, wetting agents, pharmaceutical preparations, ion exchangers, herbicides, compounds with plant growth regulatory activity; inhibitors of aminopeptidases; as structural units in peptide analogues, functioning as antibacterial agents, which inhibit bacterial cell wall biosynthesis; as structural units in peptidic phosphonylating agents that irreversibly inhibit a wide variety of serine proteases; as structural units in butyloxycarbonyl protected phosphonate esters that complex with alpha-lytic proteases; and as structural units in peptidyl phosphonate diphenyl 9 10 esters which powerfully inhibit the enzyme thrombin. ...
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:295019 |
| Date | January 1991 |
| Creators | St Claire Green, Donovan |
| Publisher | London Metropolitan University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://repository.londonmet.ac.uk/3256/ |
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