In this thesis, I describe the development of a novel method to selectively modulate neural activity cell-type selectively. Binding of Zolpidem, an allosteric modulator that enhances GABAa receptor function and the inverse agonist β-carboline, require a phenylalanine residue (F77) in the γ subunit.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:493492 |
| Date | January 2008 |
| Creators | Goetz, Thomas |
| Publisher | University of Aberdeen |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=24802 |
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