Phosphorylcholine (PC) based materials have been shown to have increased biocompatibility when compared to more established bio-implantable materials. This has been attributed to the ability of PC to mimic the cell lipid bilayer membrane, resulting in reduced protein adhesion and cellular interaction / activation. PC research has previously focused on the areas of contact lens formulation and medical device coating. This project sought to harness the biomimetic properties of PC to develop novel systems for drug delivery, with the emphasis being focused on microparticulate drug delivery.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:499068 |
| Date | January 2008 |
| Creators | Salvage, Jonathan Peter |
| Publisher | University of Brighton |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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