Stimulation of macrophages with LPS alone or in combination with IFN-y is termed 'innate' and 'classical' activation, respectively. This is associated with the expression of nos2 and p40 (IL-12/IL-23). Stimulation of macrophages with IL-4 or IL-13 is termed 'alternative' activation and is associated with expression of argI, dectin-1, mrc-1 ,fizz1 and ym1. Recent studies demonstrate that arg1 is expressed in some innate activated macrophages.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:501658 |
| Date | January 2009 |
| Creators | Menzies, Fiona Mary |
| Publisher | University of Strathclyde |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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