Upon treatment with a palladium catalyst and hydrogen gas in the presence of caesium carbonate, a wide range of exomethylenic allylic alcohols were found to afford their corresponding trisubstituted isomers. Although hydrogenation was an unavoidable competing pathway, careful monitoring of the reaction progress allowed the desired isomerised products to be obtained in moderate to excellent yields and high (E):(Z) ratios.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:558880 |
| Date | January 2012 |
| Creators | Fordred, Paul |
| Contributors | Bull, Steven |
| Publisher | University of Bath |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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