Initial direct chlorination of quinoline in the presence of aluminium trichloride, and subsequent treatment of the tetra- and pentachloroquinolines formed with phosphorus pentachloride at elevated temperatures gave heptachloroquinoline in high yield. Earlier attempts to convert quinoline directly to heptachloroquinoline using either a mixture of sulphuryl chloride, aluminium trichloride and sulphur monochloride, or phosphorus pentachloride gave mixtures of highly chlorinated quinolines which were difficult to purify.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:585766 |
| Date | January 1966 |
| Creators | Hole, Michael |
| Publisher | Durham University |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
| Source | http://etheses.dur.ac.uk/8847/ |
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