(Carboxymethyl)lysine (CML) is one of the best characterised advanced glycation-endproducts (AGEs) and is frequently used as a marker of AGE formation in foods and plasma. Nɛ-(Carboxyethyl)lysine (CEL), is also an AGE and is the homolog of CML. The focus of this research was to expand the current knowledge on dietary AGE intakes and plasma AGE status (using CML and CEL as makers of AGE formation); examining how they correlate with nutritional, biological and physical markers relating to human health. CML and CEL were found in a wide range of commonly consumed foods with cereal products and fruit and vegetables containing the highest and lowest levels, respectively for both CML and CEL. There was no significant correlation found between dietary AGE intake and plasma AGE status in healthy volunteers. Plasma AGE status was not significantly correlated with the biological and physical markers investigated in this study in either the healthy volunteers or subjects with diabetes.
| Identifer | oai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:679251 |
| Date | January 2015 |
| Creators | Hull, George Lawrence James |
| Publisher | Queen's University Belfast |
| Source Sets | Ethos UK |
| Detected Language | English |
| Type | Electronic Thesis or Dissertation |
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