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Phytochemical and biological investigation of Erigeron annuus (L.) Pers for antimicrobial activity and potential DNA gyrase inhibitors

Compositae plants of the genus Erigeron have ca. 390 species, widely distributed in most temperate regions around the world. Erigeron anl7UUS (L.) Pers. (fleabane) is one of the most valuable plants in this genus, used in Chinese foll< medicine to treat indigestion, malaria, enteritis, hepatitis and hematuria increasingly since the 1970s. However, it is not an indigenous species in China and has not been officially recorded in the Chinese Pharmacopeia. Very little research has been published on its biological activity and no activity against MRSA has been reported . In this research, whole plant material was collected in Shanghai, China and its chemical composition , antibacterial activity, DNA gyrase inhibitory activity and mutagenicity assessment were evaluated on isolated compounds and extracts.

Identiferoai:union.ndltd.org:bl.uk/oai:ethos.bl.uk:681021
Date January 2014
CreatorsZhang, Yi Fan
PublisherLondon Metropolitan University
Source SetsEthos UK
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation

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