Eva Tsui Yuen. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1995. / Includes bibliographical references (leaves 124-140). / SUMMARY / ACKNOWLEDGEMENT / Chapter CHAPTER I --- INTRODUCTION --- p.1 / Chapter CHAPTER II --- LITERATURE REVIEWS --- p.5 / Chapter 2.1 --- Anatomy and Histology of Uterine Cervix --- p.6 / Chapter 2.2 --- Premalignant and Malignant Lesions of Uterine Cervix --- p.9 / Chapter 2.2.1 --- Incidence --- p.9 / Chapter 2.2.2 --- Etiological Factors --- p.10 / Chapter 2.2.3 --- Classification and Histopathology --- p.13 / Chapter A. --- Condyloma --- p.13 / Chapter B. --- Cervical Intraepithelial Neoplasia (CIN) --- p.16 / Chapter C. --- Microinvasive Squamous Cell Carcinoma --- p.19 / Chapter D. --- Invasive Squamous Cell Carcinoma --- p.22 / Chapter E. --- Adenosquamous Carcinoma --- p.25 / Chapter F. --- Adenocarcinoma --- p.26 / Chapter 2.3 --- Human Papillomavirus (HPV) --- p.28 / Chapter 2.3.1 --- Organization of the Viral Genome --- p.28 / Chapter 2.3.2 --- Classification --- p.35 / Chapter 2.4 --- The Impact of Human Papillomavirus (HPV)in Premalignant and Malignant Lesions of Uterine Cervix --- p.35 / Chapter 2.5 --- Cervical Screening --- p.40 / Chapter 2.5.1 --- Cervical Smear --- p.40 / Chapter 2.5.2 --- Cervicography --- p.41 / Chapter 2.5.3 --- HPV Detection --- p.43 / Chapter CHAPTER III --- MATERIALS AND METHODS --- p.54 / Chapter 3.1 --- Study Population --- p.55 / Chapter 3.2 --- Specimen Collection --- p.56 / Chapter 3.3 --- Extraction of Genomic DNA --- p.56 / Chapter 3.4 --- Polymerase Chain Reaction (PCR) --- p.60 / Chapter 3.4.1 --- Oligonucleotide Primers and Positive Controls --- p.60 / Chapter 3.4.2 --- Polymerase Chain Reaction Procedure --- p.62 / Chapter A. --- PCR Optimization --- p.62 / Chapter B. --- Multiplex PCR --- p.63 / Chapter C. --- Single Primer PCR --- p.64 / Chapter 3.4.3 --- Gel Electrophoresis --- p.65 / Chapter 3.5 --- Southern-blot and Hybridization --- p.69 / Chapter 3.5.1 --- Southern-blot --- p.69 / Chapter 3.5.2 --- Nucleic Acid Hybridization --- p.71 / Chapter A. --- Oligonucleotide Probes --- p.71 / Chapter B. --- Radioactive Labelling of Probes --- p.73 / Chapter C. --- Hybridization --- p.74 / Chapter D. --- Removal of Labelled Probes --- p.77 / Chapter CHAPTER IV --- RESULTS --- p.78 / Chapter 4.1 --- Cytological Findings of Cervical Scrapes --- p.79 / Chapter 4.1.1 --- Colposcopy Group --- p.79 / Chapter 4.1.2 --- General Gynaecology Group --- p.81 / Chapter 4.1.3 --- Antenatal Group --- p.81 / Chapter 4.2 --- PCR Optimization --- p.84 / Chapter 4.3 --- Detection of HPV DNA by Multiplex PCR --- p.86 / Chapter 4.3.1 --- Colposcopy Group --- p.86 / Chapter 4.3.2 --- General Gynaecology Group --- p.89 / Chapter 4.3.3 --- Antenatal Group --- p.91 / Chapter 4.4 --- Detection of HPV DNA by Southern-blot Hybridization --- p.91 / Chapter 4.5 --- Detection of HPV DNA by Single Primer PCR --- p.104 / Chapter CHAPTER V --- DISCUSSION --- p.110 / Chapter CHAPTER VI --- CONCLUSION --- p.121 / REFERENCES --- p.124
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_320712 |
| Date | January 1995 |
| Contributors | Tsui, Eva Yuen., Chinese University of Hong Kong Graduate School. Division of Surgical Sciences. |
| Publisher | Chinese University of Hong Kong |
| Source Sets | The Chinese University of Hong Kong |
| Language | English |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, 140 leaves, [12] leaves of plates : ill. ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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