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Chemical pattern recognition of the traditional Chinese medicinal herb, epimedium.

by Kwan Yee Ting, Chris. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1998. / Includes bibliographical references (leaves 44-48). / Abstract also in Chinese. / Acknowledgements --- p.i / Abstract --- p.ii / Table of Contents --- p.v / List of Figures --- p.ix / List of Tables --- p.x / Chapter Part 1. --- Introduction --- p.1 / Chapter 1.1 --- Identification of TCM --- p.1 / Chapter 1.2 --- Chemical Pattern Recognition --- p.2 / Chapter 1.3 --- Discriminant Analysis --- p.3 / Chapter 1.4 --- Epimedium --- p.5 / Chapter 1.5 --- High Performance Liquid Chromatography --- p.6 / Chapter 1.6 --- Objectives of this work --- p.8 / Chapter Part 2. --- Chemical Analysis --- p.9 / Chapter 2.1 --- Sources of Epimedium samples --- p.9 / Chapter 2.2 --- Extraction --- p.9 / Chapter 2.2.1 --- Sample Pre-treatment --- p.9 / Chapter 2.2.2 --- Extraction Procedure --- p.9 / Chapter 2.2.3 --- Extraction Recovery --- p.11 / Chapter 2.3 --- Instrumental Analysis --- p.11 / Chapter 2.3.1 --- Chromatographic Operating Conditions --- p.12 / Chapter 2.3.2 --- Preparation of Calibration Graph --- p.12 / Chapter 2.3.3 --- Sample injection --- p.13 / Chapter 2.4 --- Results and Discussion --- p.13 / Chapter 2.4.1 --- Linearity of the Calibration Graph --- p.13 / Chapter 2.4.2 --- Development of Analysis Procedure --- p.15 / Chapter 2.4.2.1 --- Sample Pre-treatment --- p.15 / Chapter 2.4.2.2 --- Extractant --- p.15 / Chapter 2.4.2.3 --- Purification of Extract --- p.15 / Chapter 2.4.2.4 --- Extraction Time --- p.17 / Chapter 2.4.2.5 --- Solvent Gradient --- p.18 / Chapter 2.4.2.6 --- Detection --- p.19 / Chapter 2.4.3 --- Quantitative Analysis --- p.19 / Chapter 2.4.3.1 --- Extraction Recovery --- p.19 / Chapter 2.4.3.2 --- Icariin Content --- p.20 / Chapter 2.5 --- Conclusions --- p.22 / Chapter Part 3. --- Chemical Pattern Recognition --- p.24 / Chapter 3.1 --- Materials and Methods --- p.24 / Chapter 3.1.1 --- Chromatographic Results --- p.24 / Chapter 3.1.2 --- Patterns of Epimedium Samples --- p.24 / Chapter 3.1.3 --- Computer Program --- p.25 / Chapter 3.1.4 --- Variable Extraction --- p.25 / Chapter 3.1.4.1 --- Variable Extraction Parameters --- p.25 / Chapter 3.1.4.2 --- Variable Extraction Methods --- p.26 / Chapter 3.1.4.3 --- Transformation of Variables --- p.27 / Chapter 3.1.5 --- Variable Selection --- p.27 / Chapter 3.1.6 --- Predictive Power of the Recognition Model --- p.28 / Chapter 3.2 --- Results --- p.28 / Chapter 3.2.1 --- Accuracy of the Recognition Models --- p.28 / Chapter 3.2.2 --- Classification Functions --- p.29 / Chapter 3.2.3 --- Casewise Results of Recognition Model IV --- p.31 / Chapter 3.2.4 --- Plotting of the Best Two Canonical Discriminant Functions --- p.33 / Chapter 3.3 --- Discussion --- p.33 / Chapter 3.3.1 --- Meaning of Extracted Variables --- p.33 / Chapter 3.3.2 --- Limitations of Variable Extraction Methods --- p.34 / Chapter 3.3.3 --- Importance of the Variable Extraction Methods --- p.34 / Chapter 3.3.4 --- "Reasons for the Poor Performance in Recognition Models I, II and III" --- p.35 / Chapter 3.3.5 --- Selected Variables in Model IV --- p.35 / Chapter 3.3.6 --- Misclassified Samples --- p.36 / Chapter 3.3.7 --- Quality Assessment --- p.38 / Chapter 3.3.8 --- Comparison with Another Chemical Pattern Recognition Method for the Identification of Epimedium --- p.39 / Chapter 3.3.9 --- Potential Usage of the Pattern Recognition Method --- p.42 / Chapter 3.3.10 --- Advantage of the Pattern Recognition Method --- p.42 / Chapter 3.3.11 --- Disadvantage of Discriminant Analysis --- p.42 / Chapter 3.4 --- Conclusions --- p.43 / References --- p.44 / Appendix I Epimedium Species in China --- p.49 / Appendix II --- p.50 / Chapter II.1 --- Chromatograms of Samples of Epimedium sagittatum --- p.50 / Chapter II.2 --- Chromatograms of Samples of Epimedium pubescens --- p.57 / Chapter II.3 --- Chromatograms of Samples of Epimedium koreanum --- p.61 / Chapter II.4 --- Chromatograms of Samples of Epimedium leptorrhizum --- p.67 / Chapter II.5 --- Chromatograms of Samples of Epimedium wnshanese --- p.69 / Chapter II.6 --- Chromatograms of Samples of Epimedium brevicornum --- p.72 / Appendix III Log-transformed Values of Variables --- p.75

Identiferoai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_322378
Date January 1998
ContributorsKwan, Yee Ting Chris., Chinese University of Hong Kong Graduate School. Division of Chemistry.
Source SetsThe Chinese University of Hong Kong
LanguageEnglish, Chinese
Detected LanguageEnglish
TypeText, bibliography
Formatprint, x, 83 leaves : ill. (some col.) ; 30 cm.
RightsUse of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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