Kwan Pui-Chun. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2003. / Includes bibliographical references (leaves 140-155). / Abstracts in English and Chinese. / Chapter Chapter 1 --- Introduction / Chapter 1.1 --- Overview --- p.1 / Chapter 1.2 --- Iron homeostasis --- p.5 / Chapter 1.3 --- Natural Resistance Associated Marcophage Protein (Nramp) Family --- p.15 / Chapter 1.4 --- Divalent Metal Transporter 1 (DMT1) --- p.18 / Chapter 1.5 --- Iron Responsive Element (IRE) and Iron Regulatory Protein (IRP) --- p.23 / Chapter 1.6 --- Expression and localization of DMT-1 in human --- p.27 / Chapter 1.7 --- Iron and the developing feus --- p.31 / Chapter 1.8 --- Objectives of the study --- p.36 / Chapter Chapter 2 --- Materials and Method / Chapter 2.1 --- Study population --- p.37 / Chapter 2.2 --- Procedure of surgical termination of pregnancy --- p.38 / Chapter 2.3 --- Tissues collection and preparation --- p.39 / Chapter 2.4 --- Semi-quantitative Reverse Transcription-Polymerase Chain Reaction --- p.44 / Chapter 2.5 --- Immunohistochemistry --- p.49 / Chapter 2.6 --- Statistical analysis --- p.55 / Chapter Chapter 3 --- Results / Chapter 3.1 --- Description of subjects --- p.56 / Chapter 3.2 --- Existence of human DMT-1 isoforms at early pregnancy --- p.58 / Chapter 3.3 --- Relative expression of DMT-1 isoforms to β -actin mRNA expression at different week gestation --- p.67 / Chapter 3.4 --- Cellular localization of DMT-1 isoforms at early pregnancy --- p.91 / Chapter 3.5 --- Relative expression of DMT-1 proteins at early pregnancy --- p.101 / Chapter Chapter 4 --- Discussion / Chapter 4.1 --- Existence of DMT-1 at early pregnancy --- p.116 / Chapter 4.2 --- Expression of DMT-1 isoforms at early pregnancy at gene level --- p.118 / Chapter 4.3 --- Expression of DMT-1 isoforms at early pregnancy at protein level --- p.120 / Chapter 4.4 --- "Comparison expression of DMT-1 between human fetus, human adult and animal studies" --- p.121 / Chapter 4.5 --- Functional importance of DMT-1 at developing fetus at early pregnancy --- p.130 / Chapter 4.6 --- Conclusion --- p.138 / Chapter 4.7 --- Further study --- p.139 / Chapter Chapter 5 --- Reference --- p.140 / Appendix I: Calculation of EM --- p.156
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_324480 |
| Date | January 2003 |
| Contributors | Kwan, Pui-Chun., Chinese University of Hong Kong Graduate School. Division of Obstetrics and Gynaecology. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, ix, 157 leaves : ill. (some col.) ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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