by Chong Wai Sing, Wilson. / Thesis submitted in: August 2002. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2003. / Includes bibliographical references (leaves 116-126). / Abstracts in English and Chinese. / ACKNOWLEDGEMENT --- p.i / ABBREVIATION --- p.ii / ABSTRACT (Chinese & English) --- p.iii / TABLE OF CONTENT --- p.vii / INDEX FOR FIGURES --- p.x / INDEX FOR TABLES --- p.xiii / Chapter 1. --- Introduction --- p.1 / Chapter 1.1 --- "Bone-tendon junction - types, structures and functions" --- p.2 / Chapter 1.1.1 --- Indirect insertion --- p.3 / Chapter 1.1.2 --- Direct insertion --- p.3 / Chapter 1.1.3 --- Functional adaptations of insertions --- p.4 / Chapter 1.2 --- Incidence and type of injuries near insertion site --- p.5 / Chapter 1.3 --- Treatment protocol for injuries near insertion site --- p.5 / Chapter 1.3.1 --- Non-operative versus operative approach --- p.5 / Chapter 1.3.2 --- Previous studies on validations of outcomes of difference repair methods --- p.6 / Chapter 1.4 --- Modes of healing underlying different repair approach --- p.7 / Chapter 1.4.1 --- Fracture healing --- p.7 / Chapter 1.4.2 --- Tendon healing --- p.8 / Chapter 1.4.3 --- Bone-tendon healing --- p.9 / Chapter 1.5 --- Objectives --- p.9 / Chapter 2. --- Materials and Methods --- p.12 / Chapter 2.1 --- Animal model --- p.13 / Chapter 2.2 --- Experimental design --- p.13 / Chapter 2.3 --- Surgery --- p.13 / Chapter 2.3.1 --- Bone-to-bone repair --- p.14 / Chapter 2.3.2 --- Bone-to-tendon repair --- p.14 / Chapter 2.3.3 --- Tendon-to-tendon repair --- p.15 / Chapter 2.4 --- Post-operative follow-up --- p.15 / Chapter 2.4.1 --- Radiographic examination --- p.15 / Chapter 2.4.2 --- Polychrome sequential labeling --- p.16 / Chapter 2.4.2.1 --- Reagents --- p.16 / Chapter 2.4.2.2 --- Route of administration --- p.16 / Chapter 2.5 --- Sampling --- p.17 / Chapter 2.6 --- Histology --- p.17 / Chapter 2.6.1 --- Decalcification --- p.17 / Chapter 2.6.1.1 --- Tissue decalcification --- p.17 / Chapter 2.6.1.2 --- Tissue processing --- p.17 / Chapter 2.6.1.3 --- Immunohistochemistry of collagen type II and III --- p.18 / Chapter 2.6.1.3.1 --- Reagents and solution preparation --- p.18 / Chapter 2.6.1.3.2 --- Experimental procedures --- p.20 / Chapter 2.6.2 --- Undecalcification --- p.22 / Chapter 2.6.2.1 --- Specimen preparations --- p.22 / Chapter 2.6.2.2 --- Toluidine blue staining --- p.22 / Chapter 2.7 --- Mechanical test --- p.23 / Chapter 2.7.1 --- Sample preparation --- p.23 / Chapter 2.7.2 --- Embedding procedures --- p.23 / Chapter 2.7.3 --- Measurement of cross-sectional area of healing interface --- p.23 / Chapter 2.7.3.1 --- CSA for BB --- p.23 / Chapter 2.7.3.2 --- CSA for BT and TT --- p.24 / Chapter 2.7.4 --- Tensile test --- p.24 / Chapter 2.7.4.1 --- Testing procedures --- p.24 / Chapter 2.7.4.2 --- Interpretation of testing results --- p.25 / Chapter 2.7.5 --- Statistical analysis --- p.26 / Chapter 3. --- Results --- p.42 / Chapter 3.1 --- Surgical outcome --- p.43 / Chapter 3.1.1 --- Radiographic examination --- p.43 / Chapter 3.1.1.1 --- Bone-to-bone healing --- p.43 / Chapter 3.1.1.2 --- Bone-to-tendon healing --- p.44 / Chapter 3.1.2 --- Fluorochrome injection --- p.44 / Chapter 3.2 --- Histology --- p.45 / Chapter 3.2.1 --- Bone-to-bone healing --- p.45 / Chapter 3.2.1.1 --- Gross anatomy --- p.45 / Chapter 3.2.1.2 --- Microscopic examination --- p.45 / Chapter 3.2.1.3 --- Polarised light microscopy --- p.46 / Chapter 3.2.1.4 --- Fluorochrome microscopy --- p.46 / Chapter 3.2.2 --- Bone-to-tendon healing --- p.47 / Chapter 3.2.2.1 --- Gross anatomy --- p.47 / Chapter 3.2.2.2 --- Microscopic examination --- p.47 / Chapter 3.2.2.3 --- Polarised light microscopy --- p.48 / Chapter 3.2.2.4 --- Fluorochrome microscopy --- p.49 / Chapter 3.2.3 --- Tendon-to-tendon healing --- p.49 / Chapter 3.2.3.1 --- Gross anatomy --- p.49 / Chapter 3.2.3.2 --- Microscopic examination --- p.49 / Chapter 3.2.3.3 --- Polarised light microscopy --- p.50 / Chapter 3.3 --- Mechanical testing --- p.50 / Chapter 3.3.1 --- Bone-to-bone healing --- p.50 / Chapter 3.3.1.1 --- Change of cross sectional area --- p.50 / Chapter 3.3.1.2 --- Load at failure --- p.50 / Chapter 3.3.1.3 --- Strength --- p.51 / Chapter 3.3.1.4 --- Energy --- p.51 / Chapter 3.3.2 --- Bone-to-tendon healing --- p.51 / Chapter 3.3.2.1 --- Change of cross sectional area --- p.51 / Chapter 3.3.2.2 --- Load at failure --- p.52 / Chapter 3.3.2.3 --- Strength --- p.52 / Chapter 3.3.2.4 --- Energy --- p.52 / Chapter 3.3.3 --- Tendon-to-tendon healing --- p.52 / Chapter 3.3.3.1 --- Change of cross sectional area --- p.53 / Chapter 3.3.3.2 --- Load at failure --- p.53 / Chapter 3.3.3.3 --- Strength --- p.53 / Chapter 3.3.3.4 --- Energy --- p.53 / Chapter 3.3.4 --- "Comparison of healing quality among BB, BT, and TT repair" --- p.54 / Chapter 3.3.4.1 --- Change of cross sectional area --- p.54 / Chapter 3.3.4.2 --- Load at failure --- p.54 / Chapter 3.3.4.3 --- Strength --- p.54 / Chapter 3.3.4.4 --- Failure mode --- p.55 / Chapter 4. --- Discussion --- p.102 / Chapter 4.1 --- Use of goat calcaneus-Achilles junction as a bone-tendon reseach model --- p.103 / Chapter 4.2 --- "Bone-to-bone, bone-to-tendon, and tendon-to-tendon fixation" --- p.104 / Chapter 4.3 --- Histological characterization of different healing tissues --- p.105 / Chapter 4.3.1 --- Bone-to-bone healing (Fracture healing) --- p.105 / Chapter 4.3.2 --- Bone-to-tendon healing --- p.106 / Chapter 4.3.3 --- Tendon-to-tendon healing --- p.106 / Chapter 4.3.4 --- Regeneration versus repair --- p.107 / Chapter 4.4 --- Spatial and temporal expression of different type of collagen in different form of healing --- p.108 / Chapter 4.5 --- Mechanical properties of healing interface under different form of fixation --- p.108 / Chapter 4.5.1 --- Failure mode --- p.110 / Chapter 4.6 --- Limitations --- p.111 / Chapter 4.6.1 --- Goat animal model --- p.111 / Chapter 4.6.2 --- Immunohistochemistry --- p.111 / Chapter 4.7 --- Future study --- p.112 / Chapter 5. --- Conclusion --- p.113 / Chapter 6. --- References --- p.116
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_324497 |
| Date | January 2003 |
| Contributors | Chong, Wai Sing., Chinese University of Hong Kong Graduate School. Division of Orthopaedics and Traumatology. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xiii, 126 leaves : ill. (some col.) ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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