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Synthesis of novel unsymmetrical zinc(II) phthalocyanines for photodynamic therapy.

Duan Lei. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2005. / Includes bibliographical references. / Abstracts in English and Chinese. / Abstract --- p.i / Abstract (in Chinese) --- p.iii / Acknowledgement --- p.iv / Table of Contents --- p.v / List of Figures --- p.viii / List of Tables --- p.xii / List of Schemes --- p.xiii / Abbreviations --- p.xvi / Chapter Chapter 1 --- Unsymmetrical Phthalocyanines 一 An Overview / Chapter 1.1 --- Introduction --- p.1 / Chapter 1.2 --- Synthesis of A3B Phthalocyanines --- p.7 / Chapter 1.2.1 --- Statistical Condensation --- p.7 / Chapter 1.2.2 --- The Subphthalocyanine Approach --- p.13 / Chapter 1.2.3 --- Synthesis on Polymer Support --- p.16 / Chapter 1.3 --- Synthesis of A2B2 Phthalocyanines --- p.18 / Chapter 1.3.1 --- Preparation of Cross-Substituted Phthalocyanines (ABAB-type) --- p.19 / Chapter 1.3.2 --- Preparation of ´ب´بAdjacent´ح Phthalocyanines (AABB-type) --- p.21 / Chapter 1.4 --- Objectives of This Thesis --- p.24 / Chapter 1.5 --- References --- p.25 / Chapter Chapter 2 --- "Synthesis, Characterization and in vitro Photodynamic Activities of Mono-Alkoxy and Hydroxy Zinc(II) Phthalocyanines" / Chapter 2.1 --- Introduction --- p.29 / Chapter 2.2 --- "Preparation and Characterization of Unsymmetrical Zinc(II) Phthalocyanines Substituted with a 3,4,5- Tris(dodecyloxy)phenylmethyloxy Group" --- p.30 / Chapter 2.3 --- Preparation and Characterization of Halogenated Unsymmetrical Zinc(II) Phthalocyanines --- p.35 / Chapter 2.4 --- Preparation and Characterization of 2-Hydroxy Zinc(II) Phthalocyanine --- p.44 / Chapter 2.5 --- Introduction of Photodynamic Therapy (PDT) --- p.47 / Chapter 2.6 --- In vitro Photodynamic Activities of 2-Hydroxy Zinc(II) Phthalocyanine --- p.50 / Chapter 2.7 --- Conclusion --- p.52 / Chapter 2.8 --- Experimental Section --- p.52 / Chapter 2.9 --- References --- p.63 / Chapter Chapter 3 --- "Synthesis, Characterization and in vitro Photodynamic Activities of Phthalocyanines Containing N,N-Di- methylaminoethylsulfanyl Substituents" / Chapter 3.1 --- Introduction --- p.66 / Chapter 3.2 --- Preparation and Characterization of Octasubstituted Phthalocyanines --- p.67 / Chapter 3.3 --- Characterization of Disubstituted Amphiphilic Zinc(II) Phthalocyanines --- p.74 / Chapter 3.4 --- In vitro Photodynamic Activities --- p.80 / Chapter 3.5 --- Conclusion --- p.83 / Chapter 3.6 --- References --- p.90

Identiferoai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_325365
Date January 2005
ContributorsDuan, Lei., Chinese University of Hong Kong Graduate School. Division of Chemistry.
Source SetsThe Chinese University of Hong Kong
LanguageEnglish, Chinese
Detected LanguageEnglish
TypeText, bibliography
Formatprint, xvii, 91 leaves : ill. ; 30 cm.
RightsUse of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/)

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