Lau, Ting Fong Janet. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2008. / Includes bibliographical references. / Abstracts in English and Chinese. / Abstract --- p.iii / Abstract (in Chinese) --- p.v / Acknowledgment --- p.vii / Table of Contents --- p.ix / List of Figures --- p.xiii / List of Tables --- p.xix / List of Schemes --- p.xxi / Abbreviations --- p.xxiii / Chapter Chapter 1 --- Introduction / Chapter 1.1 --- General --- p.1 / Chapter 1.1.1 --- History of Phthalocyanines --- p.1 / Chapter 1.1.2 --- General Synthesis --- p.2 / Chapter 1.1.3 --- Properties and Usage of Phthalocyanines --- p.8 / Chapter 1.2 --- Phthalocyanines as Efficient Photosensitizers for Photodynamic Therapy --- p.9 / Chapter 1.2.1 --- Photophysical and Biological Mechanisms of Photodynamic Therapy --- p.10 / Chapter 1.2.2 --- Photosensitizers in Photodynamic Therapy --- p.13 / Chapter 1.2.2.1 --- First-Generation Photosensitizers --- p.13 / Chapter 1.2.2.2 --- Second-Generation Photosensitizers --- p.16 / Chapter 1.2.2.3 --- Phthalocyanine-Based Photosensitizers --- p.20 / Chapter 1.3 --- An Introduction on Supramolecular Chemistry --- p.27 / Chapter 1.3.1 --- Phthalocyanine-Based Supramolecular Systems --- p.28 / Chapter 1.3.2 --- Mixed Porphyrin-Phthalocyanine Supramolecular Assemblies --- p.31 / Chapter 1.4 --- Cyclodextrins as Building Blocks for Supramolecular Structures --- p.38 / Chapter 1.4.1 --- Background of Cyclodextrins --- p.38 / Chapter 1.4.2 --- Phthalocyanine-Cyclodextrin Supramolecular Systems --- p.41 / Chapter 1.5 --- Objectives of This Study --- p.47 / Chapter 1.6 --- References --- p.47 / Chapter Chapter 2 --- Permethylated β-Cyclodextrin Disubstituted Silicon(IV) Phthalocyanines / Chapter 2.1 --- Introduction --- p.55 / Chapter 2.2 --- Results and Discussion --- p.57 / Chapter 2.2.1 --- Preparation and Characterization --- p.57 / Chapter 2.2.2 --- Electronic Absorption and Photophysical Properties --- p.62 / Chapter 2.2.3 --- In vitro Photodynamic Activities --- p.66 / Chapter 2.3 --- Conclusion --- p.73 / Chapter 2.4 --- Experimental Section --- p.73 / Chapter 2.4.1 --- General --- p.73 / Chapter 2.4.2 --- Photophysical Measurements --- p.74 / Chapter 2.4.3 --- Synthesis --- p.75 / Chapter 2.4.4 --- Cell Lines and Culture Conditions --- p.83 / Chapter 2.4.5 --- Photocytotoxicity Assay --- p.83 / Chapter 2.4.6 --- ROS Measurements --- p.84 / Chapter 2.4.7 --- Microscopic Studies --- p.85 / Chapter 2.4.8 --- Subcellular Localization Studies --- p.85 / Chapter 2.5 --- References --- p.86 / Chapter Chapter 3 --- Unsymmetrically Substituted β-Cyclodextrin-Appended Silicon(IV) Phthalocyanines / Chapter 3.1 --- Introduction --- p.89 / Chapter 3.2 --- Results and Discussion --- p.90 / Chapter 3.2.1 --- Preparation and Characterization --- p.90 / Chapter 3.2.2 --- Electronic Absorption and Photophysical Properties --- p.94 / Chapter 3.2.3 --- In vitro Photodynamic Activities --- p.98 / Chapter 3.3 --- Conclusion --- p.107 / Chapter 3.4 --- Future Work --- p.108 / Chapter 3.5 --- Experimental Section --- p.108 / Chapter 3.5.1 --- General --- p.108 / Chapter 3.5.2 --- Synthesis --- p.109 / Chapter 3.6 --- References --- p.114 / Chapter Chapter 4 --- Construction of Mixed Phthalocyanine-Porphyrin Systems through Host-Guest Interactions in Aqueous Media / Chapter 4.1 --- Introduction --- p.117 / Chapter 4.2 --- Results and Discussion --- p.119 / Chapter 4.3 --- Conclusion --- p.132 / Chapter 4.4 --- Experimental Section --- p.132 / Chapter 4.5 --- References --- p.133 / Appendix A Determination of Binding Constants --- p.135 / Appendix B 1H and 13C{1H} NMR Spectra --- p.137 / Appendix C Mass Spectra --- p.151
| Identifer | oai:union.ndltd.org:cuhk.edu.hk/oai:cuhk-dr:cuhk_326515 |
| Date | January 2008 |
| Contributors | Lau, Ting Fong Janet., Chinese University of Hong Kong Graduate School. Division of Chemistry. |
| Source Sets | The Chinese University of Hong Kong |
| Language | English, Chinese |
| Detected Language | English |
| Type | Text, bibliography |
| Format | print, xxv, 161 leaves : ill. (some col.) ; 30 cm. |
| Rights | Use of this resource is governed by the terms and conditions of the Creative Commons “Attribution-NonCommercial-NoDerivatives 4.0 International” License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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