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Development of a Monte Carlo Simulation Model for Varian ProBeam Compact Single-Room Proton Therapy System using GEANT4

Proton therapy with pencil beam scanning technique is a novel technique to treat cancer patients due to its unique biophysical properties. However, a small error in dose calculation may lead towards undesired greater uncertainties in planed doses. This project aims to create a simulation model of Varian ProBeam Compact using the GEANT4 Monte Carlo simulation tool kit.
Experimental data from the first clinical ProBeam Compact system at South Florida Proton Therapy Institute was used to validate the simulation model. A comparison was made between the experimental and simulated Integrated Depth-Dose curves using a 2%/2mm gamma index test with 100% of points passing. The beam spot standard deviation sizes (s!) were compared using percent deviation. All simulated s! matched the experimental s! within 2.5%, except 70 and 80 MeV. The model can be used to develop a more comprehensive model as an independent dose verification tool and further investigate dose distribution. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2020. / FAU Electronic Theses and Dissertations Collection
ContributorsString, Shawn (author), Muhammad, Wazir (Thesis advisor), Shang, Charles (Thesis advisor), Florida Atlantic University (Degree grantor), Department of Physics, Charles E. Schmidt College of Science
PublisherFlorida Atlantic University
Source SetsFlorida Atlantic University
Detected LanguageEnglish
TypeElectronic Thesis or Dissertation, Text
Format57 p., online resource
RightsCopyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.,

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