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Exploration of Factors Influencing Cognition in People with Chronic Obstructive Pulmonary Disease

There has been particular interest in studying the impact of cognitive changes in individuals with Chronic Obstructive Pulmonary Disease (COPD). This population can have decreased cognition for any number of reasons including age-related declines in blood flow, disease-related declines in blood flow which affects oxygen transport to the brain, and both age and disease related declines in physical activity. PURPOSE: The purpose of the original study is to investigate the relationship between age, psychological well-being, health related quality of life (HRQL), six-minute walk distance (6MWD), seven-day physical activity recall (7DPAR), vocabulary subtest scores, pulmonary function values and five specific cognitive domains (motor speed, perceptual motor speed and sequencing, inhibitory processing, verbal fluency, and psychomotor performance) in a sample of people with COPD. METHODS: A total of 13 people with COPD aged 45 to 85 years participated in the study. There was one measure designated for each of the five cognitive domains: Motor Speed was measured by the Finger Tapping Test; Perceptual Motor Speed and Sequencing was measured by the Connections Test; Inhibitory Processing was measured by the Stroop Color Test; Verbal Fluency was measured by the Controlled Oral Word Association Test (COWAT); and Psychomotor Performance was measured by the Digit Symbol Substitution Test. Seven correlation and five multiple regression hypotheses were designed to measure the relationships among the variables. RESULTS: Significance in age (hypothesis 1) was seen in three of the five cognitive domain measures: Connections Test Numbers Letters [-.570*, p an unexpected significant relationship observed regarding the vocabulary subtest and Stroop Color, however it was in the opposite direction than the recommended hypothesis 5 [-.576*, p Hypothesis 10 regarding Inhibitory Processing, however was supported among all of the models 1-5. CONCLUSION: One consistent feature noted within the results was the significant percentages of variation accounted for by age alone or with age and 6MWD, in the cognitive domains perceptual motor speed and sequencing, inhibitory processing, and psychomotor performance. The identified relationships are consistent with the literature except for the results from BDI and vocabulary subtest. The mechanisms for decreased cognition are multiple and the present study can be regarded as a springboard for future research in the area of COPD. / A Thesis submitted to the Department of Nutrition, Food and Exercise Sciences in
partial fulfillment of the requirements for the degree of Master of Science. / Degree Awarded: Spring Semester 2005. / Date of Defense: November 30, 2004. / Aging, Cognition, Chronic Obstructive Pulmonary Disease / Includes bibliographical references. / Tonya Toole, Professor Directing Thesis; Lynn Panton, Committee Member; Sandra Faria, Committee Member.

Identiferoai:union.ndltd.org:fsu.edu/oai:fsu.digital.flvc.org:fsu_168472
ContributorsSmith, Erlinda Fay (authoraut), Toole, Tonya (professor directing thesis), Panton, Lynn (committee member), Faria, Sandra (committee member), Department of Nutrition, Food, and Exercise Science (degree granting department), Florida State University (degree granting institution)
PublisherFlorida State University
Source SetsFlorida State University
LanguageEnglish, English
Detected LanguageEnglish
TypeText, text
Format1 online resource, computer, application/pdf

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