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Oppositional Defiant Disorder Symptom Dimensions: Examining Etiological Influences and Differential Risk for Later Psychopathology

Recent research supports the multidimensionality of Oppositional Defiant Disorder (ODD), but the structure of ODD symptoms has been inconsistent across studies. Despite differences,
each model has an affective dimension, usually shown to be related to internalizing problems, and at least one behavioral dimension, usually shown to be related to externalizing problems.
While previous work has examined the etiology of overall ODD, little is known about the etiology of ODD dimensions, or the etiologic relationships between ODD dimensions and later
psychopathology. Using archival, longitudinal data from 1255 twin pairs, the current study provides a stringent comparison between competing models of ODD symptom dimensions at age 11, and
explores the relationship between the best fitting model and psychopathology assessed via diagnostic interviews at ages 17, 20, and 24. Next, a genetically informative design was used to
determine if dimensions of ODD have common and/or unique genetic and environmental influences. Finally, significant relationships found between ODD dimensions and later psychopathology
were followed-up with etiological models. Results showed a two-factor model (irritable, headstrong/hurtful) proposed by Rowe, Costello, Angold, Copeland, and Maughan (2010) and a
three-factor model (irritable, headstrong, hurtful) proposed by Stringaris and Goodman (2009a) provided the best fit to the data. However, the hurtful dimension of the three-factor model
was not uniquely related to any later psychopathology, and thus did not outperform the more parsimonious two-factor model. Consistent with hypotheses, the headstrong/hurtful dimension of
the two-factor model was correlated with externalizing problems including substance use disorder symptoms and adult antisocial behavior. The current study did not find the expected
relationships between the irritable dimension and later internalizing disorders. Twin modeling showed the irritable and headstrong/hurtful dimensions had shared and unique genetic
influences. The headstrong/hurtful dimension also had unique shared environmental influences. Further, the headstrong/hurtful dimension was related to adult disorders through shared
genetic influences. Overall, it can be concluded that symptoms of ODD, especially the headstrong/hurtful dimension, pose a significant risk for adult mental health outcomes, and common
genetic influences underlie the covariance between headstrong/hurtful symptoms and later psychopathology. / A Dissertation submitted to the Department of Psychology in partial fulfillment of the Doctor of Philosophy. / Fall Semester 2015. / October 21, 2015. / dimensions, environmental influences, genetic influences, oppositionality / Includes bibliographical references. / Jeanette Taylor, Professor Directing Dissertation; Tomi Gomory, University Representative; Sara Hart, Committee Member; Christopher Lonigan, Committee
Member; Chris Schatschneider, Committee Member.

Identiferoai:union.ndltd.org:fsu.edu/oai:fsu.digital.flvc.org:fsu_291374
ContributorsMikolajewski, Amy J. (Amy Jeanette) (authoraut), Taylor, Jeanette E. (professor directing dissertation), Gomory, Tomi (university representative), Hart, Sara (committee member), Lonigan, Christopher J. (committee member), Schatschneider, Christopher (committee member), Florida State University (degree granting institution), College of Arts and Sciences (degree granting college), Department of Psychology (degree granting department)
PublisherFlorida State University
Source SetsFlorida State University
LanguageEnglish, English
Detected LanguageEnglish
TypeText, text
Format1 online resource (83 pages), computer, application/pdf

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