The research presented in this dissertation is aimed at the characterization of normal bonded phases and the identification of important retention mechanism. First, three solutes and three solvents are chosen to represent the apices of the Snyder triangle, where each apex represents a solute or solvent whose primary interaction is either dipolar, proton accepting or proton donating. Thus, the retention information from each solute-solvent pari is unique and important retention mechanisms can be readily identified. Second, system peaks are used to characterize retention in the amino normal-bonded phase. One important result from this study is that when normal-bonded phase columns are used with high modifier concentrations, the partition model seems to be more appropriate in interpreting the retention data. Multidimensional separation procedures become especially important for complex samples consisting of numerous components. For such samples linear columns generally have inadequate power for cleanly resolving the components present, and this failure becomes increasingly pronounced as the number of components increases. Due to the unique characteristics of normal-bonded phase columns, serial coupling of any two of them seems to provide truly multidimensional separations. / Source: Dissertation Abstracts International, Volume: 53-11, Section: B, page: 5681. / Major Professor: William T. Cooper, III. / Thesis (Ph.D.)--The Florida State University, 1992.
| Identifer | oai:union.ndltd.org:fsu.edu/oai:fsu.digital.flvc.org:fsu_76812 |
| Contributors | Hsu, Cheng-Wen., Florida State University |
| Source Sets | Florida State University |
| Language | English |
| Detected Language | English |
| Type | Text |
| Format | 156 p. |
| Rights | On campus use only. |
| Relation | Dissertation Abstracts International |
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