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Novel technologies for high-throughput and high-content studies on zebrafish larvae

The zebrafish larva is an ideal candidate for in vivo high-throughput screening: it is a small vertebrate, it is optically transparent, possesses complex organs, and is easy to culture. In addition, genetic mutants and models of human diseases are widely available. Despite these attractive features there are no tools capable of screening at sufficient throughput and resolution to fully exploit the zebrafish. Here, I present a collection of technologies that enable high-throughput studies on zebrafish larvae at cellular resolution. / Engineering and Applied Sciences

Identiferoai:union.ndltd.org:harvard.edu/oai:dash.harvard.edu:1/11156677
Date08 June 2015
CreatorsPardo, Carlos
ContributorsYanik, Mehmet
PublisherHarvard University
Source SetsHarvard University
Languageen_US
Detected LanguageEnglish
TypeThesis or Dissertation
Rightsopen

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